A NOVEL SMALL MOLECULE INHIBITOR OF INFLUENZA A VIRUSES THAT TARGETS POLYMERASE FUNCTION AND INDIRECTLY INDUCES INTERFERON.

A novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferon.

Influenza viruses continue to pose a major public health threat worldwide and options for antiviral therapy are limited by the emergence of drug-resistant virus strains.The antiviral cytokine, interferon (IFN) is an moen vichy bathroom faucet essential mediator of the innate immune response and influenza viruses, like many viruses, have evolved str

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Delineation of an Isodicentric Y Chromosome in a Mosaic 45,X/46,X,idic(Y)(qter-p11.3:: p11.3-qter) Fetus by SRY Sequencing, G-banding, FISH, SKY and Study of Distribution in Different Tissues

Many factors such as genetic, developmental and hormonal are ja morant cold photos involved in mammalian sex determination.The relative importance and the mutual interactions among those factors are obscure.Study of cytogenetic mosaicism involving sex chromosomes may help to further unravel the mysterious process.We report a fetus with a mosaic kar

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ALPERS-HUTTENLOCHER SYNDROME

Alpers-Huttenlocher syndrome is a rare mitochondrial disease connected with mutations in the mitochondrial DNA replicase, polymerase gamma (POLG).The reduction of the activity within mitochondrial enzymes is connected with the reduction of replications level within the mitochondrial DNA.The disease manifests itself once the replications level reach

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